Guidelines

IV Fluid Shortage

Practice adjustments and recommendations for antimicrobial use during the critical intravenous fluid shortage due to Hurricane Helene are available here.

Quick Start, Adult

Quick Start, Pediatrics

Pre-Incisional Antimicrobial Recommendations (Adults/Pediatrics)

COVID-19 Clinical Guidance 

• Outpatient COVID-19 Treatment Guidance
• Inpatient COVID-19 Treatment Guidance 
• COVID-19 Firstline Guidance
• Emergency Room COVID-19 Treatment Guidance 
• Paxlovid DDI Guidance
• LA County | DPH | Isolation Instructions for People with COVID-19
• CDC Vaccine Clinical Considerations
• NIH Treatment Guidance

Mpox Clinical Guidance

• Process for obtaining Tecovirimat (TPOXX)

Dalbavancin Guidance 

Firstline, Syndromes – Adults

• Lung Infections
• Intra-Abdominal Infections
• Urinary Tract Infections
• Skin and Soft Tissue, Bone and Joint Infections
• Central Nervous System Infections
• Neutropenic Fever
• Sepsis of Unknown Origin 
• Bloodstream Infections
• Antimicrobial Prophylaxis

Firstline, Syndromes – Pediatrics

• Antimicrobial Prophylaxis
• Central Nervous System (CNS)
• Fever or Sepsis
• Head, Eyes, Ears, Nose, and Throat (HEENT)
• Gastrointestinal / Abdominal
• Genitourinary Tract
• Orthopedic
• Respiratory Tract
• Skin and Soft Tissue

Antibiotic Pricing

Estimated inpatient antimicrobial costs can be viewed here.

Firstline: Clinical Decisions Mobile App

Download the Firstline mobile application for detailed information including clinical guidelines, antimicrobial dosing and usage guides, and antimicrobial spectra of activity.