Resources
ASP Policies
- Antimicrobial Stewardship Program (ASP) Plan, HS 1429
- Scope of Service
- Use of Protected Anti-Infectives, HS 1444
- Outpatient Parenteral Antimicrobial Therapy (OPAT) Dosing and Monitoring Guidelines, HS IC 020
FDA Drug Shortages (Updated Bi-monthly)
UCLA Formulary Antimicrobials | Status (As of 10.14.2024) | Management |
---|---|---|
Amoxicillin oral powder for suspension |
First posted: 10/29/22 On allocation |
Consider switching to another formulation or amoxicillin clavulanate |
Amphotericin B Deoxycholate (conventional) |
First posted: 8/5/2022 Backordered |
Supply is anticipated to return 2024. Please switch to an alternative amphotericin formulation or another antifungal agent. |
Amoxicillin/Clavulanate |
First posted: 2/15/23 On allocation |
Consider switching to another formulation |
Cefdinir |
First posted: 06/29/2023 On allocation |
Suspension formulations and 300 mg capsules are on allocation; May need to switch to different capsule size or different cephalosporin |
Ciprofloxacin Injectable |
First posted: 01/08/2024 Limited supply |
May need to switch to oral ciprofloxacin or intravenous levofloxacin |
Clindamycin Vials | First posted: 09/07/2022 Limited supply |
Encourage switch to oral formulation or alternative agent |
Dicloxacillin Sodium Capsules | First posted: 07/20/2022 Backordered |
Encourage switch to another antistaphylococcal agent (i.e. amoxicillin-clavulanate, cephalexin, cefadroxil) |
Gentamicin Sulfate Injectable | First posted: 07/03/2021 Backordered |
Encourage switch to aminoglycoside or alternative agent |
Isoniazid Tablet |
First posted: 9/1/2022 Available but on allocation |
300 mg are on allocation. Patient may need to take 100 mg tablets |
Levofloxacin oral solution | First posted: 9/15/23 Backordered | May need to switch to tablet formulation |
Metronidazole Injectable | First posted: 01/03/2022 Available but on allocation |
Encourage switch to oral formulation |
Nirsevimab Intramuscular Injection (Beyfortus) | First posted: 10/23/23 Limited availability | The CDC has provided interim recommendations during this shortage to prioritize patients with the highest risk for severe RSV disease. Avoid using two 50 mg doses for infants weighing more than 5 kg (>11 lbs). For palivizumab-eligible children aged 8-10 months, use palivizumab for the 2023-2024 RSV season unless the patient is an American Indian/Alaskan native aged 8-10 months who is not eligible for palivizumab. This full guidance can be found at: https://emergency.cdc.gov/han/2023/han00499.asp |
Oseltamivir Suspension and Capsules |
First posted 11/1/2022 Available but may be on allocation |
May need to switch to a different capsule size or a different antiviral medication |
Penicillin G Benzathine or Procaine |
First posted: 02.01.23 Limited supply |
Continue to follow CDC’s Treatment recommendations. Penicillin G benzathine (Bicillin L-A®) is the only recommended treatment for pregnant people infected or exposed to syphilis. Doxycycline 100mg PO BID for two weeks (for early syphilis) or for 4 weeks (for late latent or syphilis of unknown duration) is an alternative for the treatment of non-pregnant people with a penicillin allergy. Please prioritize the use of Bicillin L-A® to treat pregnant people and babies with congenital syphilis |
Duration of Antibiotic Therapy
Data suggests that shorter courses are equivalent to longer courses with respect to achieving clinical cure and result in much fewer adverse events. Below is a review of the existing data on antibiotic durations for different infectious disease syndromes.