UCLA Health Antibiogram 2026
Contents
Note: This antibiogram is based on RRMC and SMH data. For WV, it reflects outpatient isolates only.
- Find your organism, then the column for care location.
- The number is % susceptible — darker/redder means more resistant.
- Blue PREFERRED EMPIRIC REGIMEN = best first-line choice; red ID CONSULT = call ID first.
- SDD (susceptible-dose-dependent) means the isolate is only covered at the higher CLSI dose — not susceptible at standard dosing. SDD-flagged figures (cefepime, pip-tazo) include these isolates, so true coverage at standard doses is lower than shown.
Susceptibility by organism
% susceptible≥9080–8970–7960–6950–59<50
Adults — non-urine
Six organisms behind most adult empiric decisions, split by care location.
Enterobacter cloacae complex
Outpatientn=91
98
Levofloxacin
97
Ciprofloxacin
96
TMP-SMX
Inpatientn=102
100
Meropenem
99
CefepimeSDD
PREFERRED EMPIRIC REGIMEN
91
Ciprofloxacin
91
Levofloxacin
90
Ertapenem
ICUn=65
98
Ciprofloxacin
97
Meropenem
97
Levofloxacin
95
CefepimeSDD
PREFERRED EMPIRIC REGIMEN
94
Ertapenem
Escherichia coli
Outpatientn=452
69
Amoxicillin-clavulanate
68
Levofloxacin
65
Ciprofloxacin
62
TMP-SMX
56
Oral cephalosporin
Inpatientn=506
99
Ertapenem
99
Meropenem
95
Piperacillin-tazobactamSDD
PREFERRED EMPIRIC REGIMEN
78
CefepimeSDD
71
Ceftazidime
ICUn=130
100
Meropenem
PREFERRED EMPIRIC REGIMEN
98
Ertapenem
89
Piperacillin-tazobactamSDD
72
CefepimeSDD
62
Ceftazidime
Klebsiella pneumoniae
Outpatientn=198
89
Levofloxacin
87
Amoxicillin-clavulanate
77
Ciprofloxacin
74
Oral cephalosporin
74
TMP-SMX
Inpatientn=243
98
Meropenem
PREFERRED EMPIRIC REGIMEN
97
Ertapenem
90
Piperacillin-tazobactamSDD
82
Levofloxacin
81
CefepimeSDD
ICUn=132
94
Ertapenem
94
Meropenem
PREFERRED EMPIRIC REGIMEN
81
Piperacillin-tazobactamSDD
78
Levofloxacin
73
CefepimeSDD
Proteus mirabilis
Outpatientn=169
93
Amoxicillin-clavulanate
78
Ciprofloxacin
78
Levofloxacin
74
TMP-SMX
22
Oral cephalosporin
Inpatientn=162
100
Ertapenem
100
Meropenem
98
Piperacillin-tazobactamSDD
PREFERRED EMPIRIC REGIMEN
98
Ceftazidime
96
CefepimeSDD
PREFERRED EMPIRIC REGIMEN
ICUn=29 · small
97
Ertapenem
97
Meropenem
93
Piperacillin-tazobactamSDD
PREFERRED EMPIRIC REGIMEN
93
Ceftazidime
90
CefepimeSDD
Pseudomonas aeruginosa
Outpatientn=533
81
Ciprofloxacin
78
Levofloxacin
Inpatientn=446
90
CefepimeSDD
PREFERRED EMPIRIC REGIMEN
85
Ceftazidime
85
Meropenem
81
Piperacillin-tazobactamSDD
80
Ciprofloxacin
ICUID CONSULTn=142
77
CefepimeSDD
74
Ciprofloxacin
73
Ceftazidime
68
Meropenem
66
Levofloxacin
Adults — non-urine, other gram-negatives
OP / IP / ICU are not reported separately for these organisms in the source antibiogram — figures are pooled across care locations.
Achromobacter spp.
All isolatesn=78
95
TMP-SMX
91
Meropenem
PREFERRED EMPIRIC REGIMEN
88
Piperacillin-tazobactam
62
Ceftazidime
55
Levofloxacin
Acinetobacter baumannii complex
All isolatesID CONSULTn=80
68
TMP-SMX
60
Levofloxacin
56
Ciprofloxacin
55
CefepimeSDD
55
Meropenem
Citrobacter freundii complex
All isolatesn=103
99
Meropenem
97
Ertapenem
96
CefepimeSDD
PREFERRED EMPIRIC REGIMEN
90
Levofloxacin
89
Ciprofloxacin
Klebsiella (Enterobacter) aerogenes
All isolatesn=100
98
CefepimeSDD
PREFERRED EMPIRIC REGIMEN
98
Meropenem
98
TMP-SMX
96
Ertapenem
96
Levofloxacin
Klebsiella oxytoca
All isolatesn=206
99
Ertapenem
99
Meropenem
97
CefepimeSDD
PREFERRED EMPIRIC REGIMEN
97
Levofloxacin
96
Piperacillin-tazobactam
PREFERRED EMPIRIC REGIMEN
Morganella morganii
All isolatesn=83
100
Piperacillin-tazobactam
PREFERRED EMPIRIC REGIMEN
100
CefepimeSDD
PREFERRED EMPIRIC REGIMEN
99
Ertapenem
99
Meropenem
89
Ceftazidime
Serratia marcescens
All isolatesn=226
100
CefepimeSDD
PREFERRED EMPIRIC REGIMEN
100
Meropenem
99
Ertapenem
99
TMP-SMX
98
Ceftazidime
Stenotrophomonas maltophilia
All isolatesID CONSULTn=111
No routinely reported agent with a susceptibility figure — see 02 · MDR organisms for salvage-agent data.
Adults — urine
Urinary isolates only.
Enterobacter cloacae complex
Outpatientn=236
93
Ciprofloxacin
92
Levofloxacin
90
TMP-SMX
51
Nitrofurantoin
Inpatientn=52
99
CefepimeSDD
99
Meropenem
88
Ciprofloxacin
88
Levofloxacin
87
Ertapenem
Escherichia coli
Outpatientn=9692
97
Nitrofurantoin
87
Amoxicillin-clavulanate
86
Oral cephalosporin
74
TMP-SMX
71
Levofloxacin
Inpatientn=1094
99
Ertapenem
99
Meropenem
96
Nitrofurantoin
80
Amoxicillin-clavulanate
74
Ceftriaxone
Klebsiella pneumoniae
Outpatientn=1657
87
Oral cephalosporin
86
TMP-SMX
84
Ciprofloxacin
84
Levofloxacin
32
Nitrofurantoin
Inpatientn=291
99
Ertapenem
99
Meropenem
78
Ceftriaxone
78
TMP-SMX
77
Oral cephalosporin
Proteus mirabilis
Outpatientn=944
97
Amoxicillin-clavulanate
94
Oral cephalosporin
88
Ciprofloxacin
88
Levofloxacin
82
TMP-SMX
Inpatientn=189
99
Ertapenem
99
Meropenem
93
Amoxicillin-clavulanate
82
Ceftriaxone
78
Oral cephalosporin
Pseudomonas aeruginosa
Outpatientn=490
89
Ciprofloxacin
84
Levofloxacin
Inpatientn=143
89
CefepimeSDD
88
Meropenem
85
Ceftazidime
85
Ciprofloxacin
83
Piperacillin-tazobactamSDD
Adults — gram-positive cocci
Resistance rates only; see the printed antibiogram for the full gram-positive susceptibility tables.
MRSA and VRE rates — adults
S. aureus · OP n=1886
76%MSSA24%MRSA
S. aureus · IP n=830
64%MSSA36%MRSA
S. aureus · ICU n=236
65%MSSA35%MRSA
E. faecalis n=683
96%VSE4%VRE
E. faecium n=223
40%VSE60%VRE
Enterococcus spp. (other) n=48
58%VSE42%VRE
Paediatrics (≤21 y) — non-urine
Pooled across care locations.
Enterobacter cloacae complex
All isolatesn=29 · small
99
Ertapenem
99
Meropenem
97
Cefepime
PREFERRED EMPIRIC REGIMEN
96
TMP-SMX
93
Ciprofloxacin
Escherichia coli
All isolatesn=68
99
Ertapenem
99
Meropenem
94
Piperacillin-tazobactam
PREFERRED EMPIRIC REGIMEN
90
Cefepime
88
Ceftazidime
Klebsiella pneumoniae
All isolatesn=42
99
Meropenem
PREFERRED EMPIRIC REGIMEN
95
Ertapenem
90
Piperacillin-tazobactam
90
Cefepime
86
Ceftazidime
Serratia marcescens
All isolatesn=35
99
Piperacillin-tazobactam
PREFERRED EMPIRIC REGIMEN
99
Cefepime
PREFERRED EMPIRIC REGIMEN
99
Ertapenem
99
Meropenem
97
TMP-SMX
Pseudomonas aeruginosa
All isolatesn=94
95
Cefepime
PREFERRED EMPIRIC REGIMEN
94
Ceftazidime
93
Piperacillin-tazobactam
PREFERRED EMPIRIC REGIMEN
90
Meropenem
89
Ciprofloxacin
Paediatrics (≤21 y) — urine
Urinary isolates only.
Enterobacter cloacae complex
All isolatesn=24 · small
99
Cefepime
99
Meropenem
92
Ciprofloxacin
91
Ertapenem
83
TMP-SMX
Escherichia coli
All isolatesn=904
99
Ertapenem
99
Meropenem
98
Nitrofurantoin
93
Ceftriaxone
91
Oral cephalosporin
Klebsiella pneumoniae
All isolatesn=95
99
Ertapenem
99
Meropenem
91
Amoxicillin-clavulanate
88
Ceftriaxone
87
Oral cephalosporin
Proteus mirabilis
All isolatesn=123
99
Oral cephalosporin
99
Ceftriaxone
99
Ertapenem
99
Meropenem
97
Ciprofloxacin
Pseudomonas aeruginosa
All isolatesn=14 · small
99
Cefepime
99
Ceftazidime
99
Meropenem
93
Ciprofloxacin
Paediatrics (≤21 y) — gram-positive cocci
Resistance rates only; see the printed antibiogram for the full gram-positive susceptibility tables.
MRSA and VRE rates — paediatrics
S. aureus · OP n=538
88%MSSA12%MRSA
S. aureus · IP n=113
87%MSSA13%MRSA
E. faecalis n=43
99%VSE1%VRE
E. faecium n=5 · small
60%VSE40%VRE
Multidrug-resistant organisms
Tables 6 & 7
Multidrug-resistant gram-negatives — salvage agents
All sources. These are the isolates where empiric choices have already failed. Denominators differ by agent for CRE — not every isolate was tested against every drug.
| Organism | Amikacin | Gentamicin | Ciprofloxacin | Piperacillin-tazobactam | Cefepime | Ceftazidime | Ceftazidime-avibactam | Ceftolozane-tazobactam | Meropenem-vaborbactam | Minocycline | TMP-SMX | Tigecyclinenot for bacteraemia | Eravacyclinenot for bacteraemia | Omadacyclinenot for bacteraemia |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Carbapenem-resistant Enterobacterales (CRE) n=349 | 83 n=349 |
— | — | — | — | — | 94 n=349 |
77 n=349 |
77 n=66 |
— | — | 87 n=70 |
79 n=66 |
80 n=66 |
| P. aeruginosa — imipenem OR meropenem resistant n=292 | 91 n=292 |
— | 50 n=292 |
49 n=292 |
63 n=292 |
59 n=292 |
90 n=292 |
91 n=292 |
— | R | R | — | — | — |
| P. aeruginosa — imipenem AND meropenem resistant n=171 | 89 n=171 |
— | 38 n=171 |
29 n=171 |
47 n=171 |
41 n=171 |
87 n=171 |
89 n=171 |
— | R | R | — | — | — |
| A. baumannii complex — meropenem resistant n=42 | 43 n=42 |
21 n=42 |
10 n=42 |
2 n=42 |
2 n=42 |
5 n=42 |
— | — | — | 50 n=42 |
36 n=42 |
— | — | — |
Restricted formulary — ID consult required. These agents are not released by pharmacy without Infectious Diseases approval. Plan the consult at the same time you plan the culture, not after the result returns.
Amikacin for P. aeruginosa applies to urine isolates only.
Yeasts
Candida albicans n=344 FLUCONAZOLE PREFERRED
FLUCONAZOLE
S 96% ≤2R 4% ≥8
MICAFUNGIN
S 99% ≤0.25
Candida glabrata n=207
FLUCONAZOLE
SDD 87% <32R 13% ≥64
MICAFUNGIN
S 99% ≤0.06I 1% 0.12
Candida parapsilosis n=86 FLUCONAZOLE PREFERRED
FLUCONAZOLE
S 95% ≤2R 5% ≥8
MICAFUNGIN
S 99% ≤2
Candida tropicalis n=57 FLUCONAZOLE PREFERRED
FLUCONAZOLE
S 96% ≤2R 4% ≥8
MICAFUNGIN
S 99% ≤0.25
Candida krusei n=34
FLUCONAZOLE
Intrinsically resistant to fluconazole.
MICAFUNGIN
S 99% ≤0.25
Candida guilliermondii n=10
FLUCONAZOLE
No interpretable result
MICAFUNGIN
S 99% ≤2
2024–2025 isolates. Breakpoints in µg/mL. Not all isolates were tested against all agents.